Basic Information
| LncRNA/CircRNA Name | UCA1 |
| Synonyms | UCA1, CUDR, LINC00178, NCRNA00178, UCAT1, onco-lncRNA-36 |
| Region | GRCh38_19:15828206-15836326 |
| Ensemble | ENSG00000214049 |
| Refseq | NR_015379 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | colorectal cancer |
| ICD-0-3 | C19.9 |
| Methods | qPCR |
| Sample | colorectal cancer tissues, serum, cell lines (SW480, HT-29 and LS 175T) |
| Expression Pattern | up-regulated |
| Function Description | The expression tendency of the five up-regulated lncRNAs (UCA1, CRNDE, H19, ZFAS1 and BLACAT1) and two down-regulated lncRNAs (DPP10-AS1 and HAGLR) were same as the results of microarray data |
| Pubmed ID | 28406230 |
| Year | 2017 |
| Title | Meta-signature LncRNAs serve as novel biomarkers for colorectal cancer: integrated bioinformatics analysis, experimental validation and diagnostic evaluation |
External Links
| Links for UCA1 | GenBank HGNC NONCODE |
| Links for colorectal cancer | OMIM COSMIC |