Basic Information
| LncRNA/CircRNA Name | UCA1 |
| Synonyms | UCA1, CUDR, LINC00178, NCRNA00178, UCAT1, onco-lncRNA-36 |
| Region | GRCh38_19:15828206-15836326 |
| Ensemble | ENSG00000214049 |
| Refseq | NR_015379 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | colon cancer |
| ICD-0-3 | C18 |
| Methods | qPCR etc. |
| Sample | colon cancer tissues |
| Expression Pattern | up-regulated |
| Function Description | Compared with adjacent normal tissues, UCA1 was significantly upregulated in colon cancer tissues, especially in cases with LNM and advanced TNM stages. High UCA1 expression was associated with LMN, higher pT category, and advanced TNM stages. Patients with high UCA1 expression had worse survival time than those with low UCA1 expression. Furthermore, plasma levels of UCA1 in colon cancer patients were significantly higher than those of controls. |
| Pubmed ID | 26885155 |
| Year | 2015 |
| Title | Clinical significance of urothelial carcinoma associated 1 in colon cancer. |
External Links
| Links for UCA1 | GenBank HGNC NONCODE |
| Links for colon cancer | OMIM COSMIC |