Basic Information
| LncRNA/CircRNA Name | UCA1 |
| Synonyms | UCA1, CUDR, LINC00178, NCRNA00178, UCAT1, onco-lncRNA-36 |
| Region | GRCh38_19:15828206-15836326 |
| Ensemble | ENSG00000214049 |
| Refseq | NR_015379 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | multiple myeloma |
| ICD-0-3 | C42.1 |
| Methods | qPCR |
| Sample | cell line (BMPC) |
| Expression Pattern | differential expression |
| Function Description | UCA1 levels correlated with albumin and monoclonal immunoglobulin serum levels, cytogenetic aberrations, and survival of MM patients.higher levels of UCA1 were significantly associated with worse OS of MM patients in the time period of 1-4 years. |
| Pubmed ID | 28543758 |
| Year | 2017 |
| Title | Deregulated expression of long non-coding RNA UCA1 in multiple myeloma |
External Links
| Links for UCA1 | GenBank HGNC NONCODE |
| Links for multiple myeloma | OMIM COSMIC |