Basic Information
| LncRNA/CircRNA Name | UCA1 |
| Synonyms | UCA1, CUDR, LINC00178, NCRNA00178, UCAT1, onco-lncRNA-36 |
| Region | GRCh38_19:15828206-15836326 |
| Ensemble | ENSG00000214049 |
| Refseq | NR_015379 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | 2 | ||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | prostate cancer |
| ICD-0-3 | C61.9 |
| Methods | Western blotting, Luciferase Reporter Assay, RIP, qRT-PCR |
| Sample | prostate cancer tissues,serum samples |
| Expression Pattern | up-regulated |
| Function Description | UCA1 Was Upregulated in Human PCa Tissues and Cell Lines.UCA1 Promoted the Cell Proliferation of PCa in Vitro.UCA1 Promotes PCa Tumorigenesis In Vivo.Through the UCA1/miR-143/MYO6 axis, UCA1 performed specific regulatory roles in the proliferation and progression of PCa. |
| Pubmed ID | 31954329 |
| Year | 2020 |
| Title | lncRNA UCA1 Functions as a ceRNA to Promote Prostate Cancer Progression via Sponging miR143 |
External Links
| Links for UCA1 | GenBank HGNC NONCODE |
| Links for prostate cancer | OMIM COSMIC |