Basic Information
| LncRNA/CircRNA Name | UCA1 |
| Synonyms | UCA1, CUDR, LINC00178, NCRNA00178, UCAT1, onco-lncRNA-36 |
| Region | GRCh38_19:15828206-15836326 |
| Ensemble | ENSG00000214049 |
| Refseq | NR_015379 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | prostate cancer |
| ICD-0-3 | C61.9 |
| Methods | qPCR, Luciferase reporter assay, RIP, Western blot |
| Sample | prostatic hyperplasia tissues,cell lines(PC-3, LnCaP,DU-145,RWPE-1) |
| Expression Pattern | up-regulated |
| Function Description | The up-regulation of UCA1 in PC-3 cells significantly impaired the inhibitory effect of miR204 on CXCR4 expression |
| Pubmed ID | 30940776 |
| Year | 2019 |
| Title | LncRNA UCA1 acts as a sponge of miR-204 to up-regulate CXCR4 expression and promote prostate cancer progression. |
External Links
| Links for UCA1 | GenBank HGNC NONCODE |
| Links for prostate cancer | OMIM COSMIC |