Basic Information
| LncRNA/CircRNA Name | uc.8+ |
| Synonyms | NA |
| Region | GRCh38_19:76163-77686 |
| Ensemble | ENSG00000282591 |
| Refseq | NR_026820 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | bladder cancer |
| ICD-0-3 | C67 |
| Methods | Microarray, qPCR, RNAi, Cell proliferation assay etc. |
| Sample | bladder cancer tissues, cell lines (J82 and RT112) |
| Expression Pattern | up-regulated |
| Function Description | The results showed an increase of 6.5 fold for uc.8+, an increase of 2.45 fold for uc.339+, a decrease of 0.105 fold for uc.195+, and a decrease of 0.25 fold for uc.217+A in BlCa tissues compared with NBE. These results are consistent with the trend shown by microarray analysis results and indicate the primary role that uc.8+ may have in BlCa onset and progression. |
| Pubmed ID | 26943042 |
| Year | 2016 |
| Title | Long non-coding RNA containing ultraconserved genomic region 8 promotes bladder cancer tumorigenesis |
External Links
| Links for uc.8+ | GenBank HGNC NONCODE |
| Links for bladder cancer | OMIM COSMIC |