Basic Information
| LncRNA/CircRNA Name | Uc.63+ |
| Synonyms | NA |
| Region | NA |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | gastric cancer |
| ICD-0-3 | C16 |
| Methods | qPCR, Western blot, in vitro knockdown etc |
| Sample | GC tissues and corresponding normal stomach tissues,cell lines(MKN-1, MKN-7, MKN-45, MKN-74, HSC-57, TMK-1, KATO-III, HSC-39, HSC-44PE, and HSC-44As3) |
| Expression Pattern | up-regulated |
| Function Description | The upregulation of Uc.63+ was significantly correlated with advanced clinico-pathological features. Knockdown of Uc.63+??ignificantly repressed GC cell growth and migration, whereas overexpression of Uc.63+??onversely promoted those of GC cells. |
| Pubmed ID | 32323025 |
| Year | 2020 |
| Title | Uc.63+ contributes to gastric cancer progression through regulation of NF-kB signaling. |
External Links
| Links for Uc.63+ | GenBank HGNC NONCODE |
| Links for gastric cancer | OMIM COSMIC |