Basic Information
| LncRNA/CircRNA Name | uc.388 |
| Synonyms | NA |
| Region | NA |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | colorectal cancer |
| ICD-0-3 | C19.9 |
| Methods | qPCR etc. |
| Sample | CRC tissues |
| Expression Pattern | down-regulated |
| Function Description | Expression levels of uc.73 and uc.388 were significantly decreased in CRC tissue, and uc.73 indicated a positive correlation with overall survival. The lower expression of uc.388 was associated with the distal location of CRC. Our preliminary results suggest that uc.73 and uc.388 could be potential diagnostic and prognostic biomarkers in CRC patients. |
| Pubmed ID | 22328099 |
| Year | 2012 |
| Title | Expression levels of transcribed ultraconserved regions uc.73 and uc.388 are altered in colorectal cancer. |
External Links
| Links for uc.388 | GenBank HGNC NONCODE |
| Links for colorectal cancer | OMIM COSMIC |