Basic Information
| LncRNA/CircRNA Name | UBE2CP3 |
| Synonyms | NA |
| Region | GRCh38_4:57072683-57073132 |
| Ensemble | ENSG00000250384 |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | hepatocellular carcinoma |
| ICD-0-3 | C22.0 |
| Methods | Microarray, qPCR, Western blot etc. |
| Sample | tissues, cell lines (HepG2, SMMC-7721) |
| Expression Pattern | up-regulated |
| Function Description | Clinical data showed that high levels of lncRNA UBE2CP3 were correlated with poor prognosis in HCC patients. Functional studies demonstrated that over-expression of lncRNA UBE2CP3 promoted cell invasion and migration in vitro and in vivo.Our results suggest that lncRNA UBE2CP3 promotes the metastasis of HCC and that serum lncRNA UBE2CP3 may be a new biomarker for the diagnosis of HCC. |
| Pubmed ID | 29029437 |
| Year | 2017 |
| Title | Long non-coding RNA UBE2CP3 promotes tumor metastasis by inducing epithelial-mesenchymal transition in hepatocellular carcinoma |
External Links
| Links for UBE2CP3 | GenBank HGNC NONCODE |
| Links for hepatocellular carcinoma | OMIM COSMIC |