Basic Information
| LncRNA/CircRNA Name | CASC19 |
| Synonyms | NA |
| Region | GRCh38_8:127072694-127227541 |
| Ensemble | ENSG00000254166 |
| Refseq | NR_120364 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | clear cell renal cell carcinoma |
| ICD-0-3 | C64.9 |
| Methods | Western blot, RIP, Luciferase Reporter Assay, in vitro knockdown |
| Sample | ccRCC tissues,cell lines(786-O, Caki-1, and A498) |
| Expression Pattern | up-regulated |
| Function Description | CASC19 was overexpressed in ccRCC tissues and cell lines. High expression of CASC19 was closely associated with unfavorable clinicopathological parameters and predicted negative clinical outcomes in patients with ccRCC. |
| Pubmed ID | 32273759 |
| Year | 2020 |
| Title | Long Non-Coding RNA CASC19 Sponges microRNA-532 and Promotes Oncogenicity of Clear Cell Renal Cell Carcinoma by Increasing ETS1 Expression |
External Links
| Links for CASC19 | GenBank HGNC NONCODE |
| Links for clear cell renal cell carcinoma | OMIM COSMIC |