Basic Information
| LncRNA/CircRNA Name | TUG1 |
| Synonyms | TUG1, LINC00080, NCRNA00080, TI-227H |
| Region | GRCh38_22:30969245-30979395 |
| Ensemble | ENSG00000253352 |
| Refseq | NR_002323 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | gastric cancer |
| ICD-0-3 | C16 |
| Methods | qPCR, Western blot, Luciferase reporter assay etc. |
| Sample | Gastric carcinoma tissues, cell lines (GES-1, Bgastric cancer-823, Mgastric cancer-803, Sgastric cancer-7901, MKN28) |
| Expression Pattern | up-regulated |
| Function Description | downregulation of miR-381 by lncRNA-TUG1 promoted the metastasis of GC cells by inhibiting SOX4. |
| Pubmed ID | 28927144 |
| Year | 2017 |
| Title | MiR-381 inhibits migration and invasion in human gastric carcinoma through downregulatedting SOX4 |
External Links
| Links for TUG1 | GenBank HGNC NONCODE |
| Links for gastric cancer | OMIM COSMIC |