Basic Information
LncRNA/CircRNA Name | TUG1 |
Synonyms | TUG1, LINC00080, NCRNA00080, TI-227H |
Region | GRCh38_22:30969245-30979395 |
Ensemble | ENSG00000253352 |
Refseq | NR_002323 |
Classification Information
Regulatory Mechanism | Biological Function | Clinical Application | |||
---|---|---|---|---|---|
TF | Immune | Survival | |||
Enhancer | Apoptosis | Drug | |||
Variant | Cell Growth | Circulating | |||
MiRNA | EMT | Metastasis | |||
Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
Cancer Name | urothelial cancer |
ICD-0-3 | NA |
Methods | qPCR |
Sample | urothelial carcinoma tissues, cell lines (VM-CUB1, SW-1710, HT-1376, 5637, and BFTC-905) |
Expression Pattern | differential expression |
Function Description | Altered expression of individual lncRNAs was associated with overall survival, but not consistently between both patient cohorts. Interestingly, lower expression of TUG1 in a subset of UC patients with muscle-invasive tumours was significantly correlated with worse OS in both cohorts. |
Pubmed ID | 28430799 |
Year | 2017 |
Title | Diagnostic and prognostic value of long noncoding RNAs as biomarkers in urothelial carcinoma |
External Links
Links for TUG1 | GenBank HGNC NONCODE |
Links for urothelial cancer | OMIM COSMIC |