Basic Information
| LncRNA/CircRNA Name | TUG1 |
| Synonyms | TUG1, LINC00080, NCRNA00080, TI-227H |
| Region | GRCh38_22:30969245-30979395 |
| Ensemble | ENSG00000253352 |
| Refseq | NR_002323 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | tongue squamous cell carcinoma |
| ICD-0-3 | C02 |
| Methods | qPCR etc. |
| Sample | cell lines (CAL-27, SCC-9) |
| Expression Pattern | up-regulated |
| Function Description | TUG1 significantly contributes to TSCC development.Silencing TUG1 could inhibit TSCC proliferation and modulate the cell cycle.Based on our findings,TUG1 may be a potential therapeutic target in TSCC;additional research regarding mechanisms associated with TUG1 in TSCC should be performed in the future. |
| Pubmed ID | 28597931 |
| Year | 2017 |
| Title | An in vitro study of the long non-coding RNA TUG1 in tongue squamous cell carcinoma |
External Links
| Links for TUG1 | GenBank HGNC NONCODE |
| Links for tongue squamous cell carcinoma | OMIM COSMIC |