Basic Information
| LncRNA/CircRNA Name | TUG1 |
| Synonyms | NA |
| Region | GRCh38_22:30969245-30979395 |
| Ensemble | ENSG00000253352 |
| Refseq | NR_002323 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | hepatocellular carcinoma |
| ICD-0-3 | C22.0 |
| Methods | qPCR, Western blot |
| Sample | blood |
| Expression Pattern | up-regulated |
| Function Description | CASC2 was down regulated in HCC/HCV patients while TUG1 was overexpressed in relation to HCV and control group indicating their antagonistic effect. This can suggest their role in the pathogenesis of HCC on top of HCV. Their expression was correlated to BCLC stage and serum AFP level. |
| Pubmed ID | 31301261 |
| Year | 2019 |
| Title | Long non-coding RNAs (CASC2 and TUG1) in hepatocellular carcinoma: Clinical significance |
External Links
| Links for TUG1 | GenBank HGNC NONCODE |
| Links for hepatocellular carcinoma | OMIM COSMIC |