Basic Information
| LncRNA/CircRNA Name | TUG1 |
| Synonyms | NA |
| Region | GRCh38_22:30969245-30979395 |
| Ensemble | ENSG00000253352 |
| Refseq | NR_002323 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | anticancer drugs | |
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | prostate cancer |
| ICD-0-3 | C61.9 |
| Methods | qPCR, Western blot |
| Sample | Prostate Cancer Tissues,cell lines (LNCaP, DU145,PC3,P69) |
| Expression Pattern | up-regulated |
| Function Description | In this study, we found that TUG1 was upregulated both in prostate cancer samples and cells. TUG1 promotes endometrial cancer development via inhibiting miR-299 and miR-34a-5p |
| Pubmed ID | 30964164 |
| Year | 2019 |
| Title | Long noncoding RNA TUG1 promotes progression via upregulating DGCR8 in prostate cancer. |
External Links
| Links for TUG1 | GenBank HGNC NONCODE |
| Links for prostate cancer | OMIM COSMIC |