Basic Information
| LncRNA/CircRNA Name | TUG1 |
| Synonyms | NA |
| Region | GRCh38_22:30969245-30979395 |
| Ensemble | ENSG00000253352 |
| Refseq | NR_002323 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | acute myeloid leukemia |
| ICD-0-3 | NA |
| Methods | qRT-PCR, Western blot |
| Sample | AML bone marrow,cell lines |
| Expression Pattern | up-regulated |
| Function Description | Silencing of lncRNA TUG1 induces a cytotoxic effect on AML cell lines through sponging miR-193a-5p and the suppression of Rab10. |
| Pubmed ID | 32103996 |
| Year | 2020 |
| Title | LncRNA TUG1 Regulates Cell Viability and Death by Regulating miR-193a-5p/Rab10 Axis in Acute Myeloid Leukemia |
External Links
| Links for TUG1 | GenBank HGNC NONCODE |
| Links for acute myeloid leukemia | OMIM COSMIC |