Basic Information
| LncRNA/CircRNA Name | TUC338 |
| Synonyms | NA |
| Region | GRCh38_12:53464468-53465057 |
| Ensemble | ENSG00000282977 |
| Refseq | NR_109828 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | lung cancer |
| ICD-0-3 | C34 |
| Methods | qPCR, Western blot |
| Sample | lung cancer tissues, cell lines (A549, H1755, SK-MES-1, H1299) |
| Expression Pattern | up-regulated |
| Function Description | the expression of TUC338 was correlated with the overall survival, tumor size and lymph node metastasis in patients, but not with age and gender.the activity of lung cancer cells was decreased, as well as the invasion ability after interference with TUC338.TUC338 can promote the development of lung cancer through regulating MAPK pathway. |
| Pubmed ID | 29424901 |
| Year | 2018 |
| Title | LncRNA TUC338 promotes invasion of lung cancer by activating MAPK pathway. |
External Links
| Links for TUC338 | GenBank HGNC NONCODE |
| Links for lung cancer | OMIM COSMIC |