Basic Information
| LncRNA/CircRNA Name | TUBA4B |
| Synonyms | TUBA4B, TUBA4 |
| Region | GRCh38_2:219253243-219272188 |
| Ensemble | ENSG00000243910 |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | non small cell lung cancer |
| ICD-0-3 | C34 |
| Methods | qPCR, Cell proliferation assay etc. |
| Sample | NSCLC tissues, cell lines (SPCA-1, NCI-H1299, A549, NCI-H441, LTEP-a2) |
| Expression Pattern | down-regulated |
| Function Description | We found TUBA4B was lower expressed in NSCLC and five cell lines. The lower expression of TUBA4B was remarkably correlated with advanced TNM stage and lymph node metastasis and served as a predictor for overall survival of NSCLC. |
| Pubmed ID | 27411923 |
| Year | 2016 |
| Title | Low Expression LncRNA TUBA4B is a Poor Predictor of Prognosis and Regulates Cell Proliferation in Non-Small Cell Lung Cancer. |
External Links
| Links for TUBA4B | GenBank HGNC NONCODE |
| Links for non small cell lung cancer | OMIM COSMIC |