Basic Information
LncRNA/CircRNA Name | TRPM2-AS |
Synonyms | NA |
Region | GRCh38_21:44414588-44425272 |
Ensemble | ENSG00000230061 |
Refseq | NR_109964 |
Classification Information
Regulatory Mechanism | Biological Function | Clinical Application | |||
---|---|---|---|---|---|
TF | Immune | Survival | |||
Enhancer | Apoptosis | apoptosis | Drug | ||
Variant | Cell Growth | Circulating | |||
MiRNA | EMT | Metastasis | |||
Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
Cancer Name | breast cancer |
ICD-0-3 | C50 |
Methods | RNA-seq, qPCR, Luciferase reporter assay, Western blot |
Sample | BC tissues,cell line (MCF-10A) |
Expression Pattern | up-regulated |
Function Description | Both TRPM2-AS and PYCR1 were significantly up-regulated yet miR-140-3p was significantly down-regulated in BC tissues compared with normal adjacent tissues. |
Pubmed ID | 30810442 |
Year | 2019 |
Title | Identification of lncRNA TRPM2-AS/miR-140-3p/PYCR1 axis's proliferates and anti-apoptotic effect on breast cancer using co-expression network analysis. |
External Links
Links for TRPM2-AS | GenBank HGNC NONCODE |
Links for breast cancer | OMIM COSMIC |