Basic Information
| LncRNA/CircRNA Name | CASC15 |
| Synonyms | NA |
| Region | GRCh38_6:21664772-22368328 |
| Ensemble | ENSG00000272168 |
| Refseq | NR_015410 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | bladder cancer |
| ICD-0-3 | C67 |
| Methods | qPCR, Luciferase reporter assay etc |
| Sample | BLCA tissues,cell lines (BIU, J82, SW780, UMUC3) |
| Expression Pattern | up-regulated |
| Function Description | CASC15 expression was upregulated in BLCA tissue samples. Moreover, CASC15 downregulated the miR-130b-3p expression and promoted cell migration and invasion in BLCA in vitro. The rescue experiments also revealed that the inhibitory effects by the silence of CASC15 could be reversed through the inhibition of miR-130b-3p. |
| Pubmed ID | 31799648 |
| Year | 2019 |
| Title | LncRNA CASC15 Functions as an Oncogene by Sponging miR-130b-3p in Bladder Cancer |
External Links
| Links for CASC15 | GenBank HGNC NONCODE |
| Links for bladder cancer | OMIM COSMIC |