Basic Information
| LncRNA/CircRNA Name | TRERNA |
| Synonyms | TRERNA1, LINC00651, treRNA |
| Region | GRCh38_20:50040716-50041504 |
| Ensemble | ENSG00000231265 |
| Refseq | NR_051976 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | hepatocellular carcinoma |
| ICD-0-3 | C22.0 |
| Methods | qPCR, RNAi, Western blot, Dual luciferase reporter assay etc. |
| Sample | cell lines (HepG2, Huh7) |
| Expression Pattern | up-regulated |
| Function Description | We further examined the expression profile of treRNA and miR-190a in 24 pairs of HCC tissues and adjacent normal tissues. miR-190a exhibited a significantly low expression in HCC tissues compared to adjacent normal tissues. Meanwhile, an elevated expression of treRNA was observed in HCC tissue compared to adjacent normal tissue. |
| Pubmed ID | 26608035 |
| Year | 2015 |
| Title | miR-190a inhibits epithelial-mesenchymal transition of hepatoma cells via targeting the long non-coding RNA treRNA. |
External Links
| Links for TRERNA | GenBank HGNC NONCODE |
| Links for hepatocellular carcinoma | OMIM COSMIC |