Basic Information
| LncRNA/CircRNA Name | TP73-AS1 |
| Synonyms | TP73-AS1, KIAA0495, PDAM |
| Region | GRCh38_1:3735601-3747336 |
| Ensemble | ENSG00000227372 |
| Refseq | NR_033708 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | glioblastoma multiforme |
| ICD-0-3 | NA |
| Methods | qPCR, RNAi, MTT assay etc. |
| Sample | cell line (U87) |
| Expression Pattern | differential expression |
| Function Description | Knockdown of TP73-AS1 could not only reduce the expression of RFX1, an mRNA of this triplet, but also induce apoptosis in U87 cells. |
| Pubmed ID | 28168356 |
| Year | 2017 |
| Title | Identifying survival-associated modules from the dysregulated triplet network in glioblastoma multiforme. |
External Links
| Links for TP73-AS1 | GenBank HGNC NONCODE |
| Links for glioblastoma multiforme | OMIM COSMIC |