Basic Information
| LncRNA/CircRNA Name | TIRY |
| Synonyms | NA |
| Region | NA |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | oral squamous cell carcinoma |
| ICD-0-3 | C06.9 |
| Methods | qRT-PCR, Western blot |
| Sample | OSCC tissues |
| Expression Pattern | up-regulated |
| Function Description | TIRY overexpression in cancer-associated fibroblasts activated the Wnt/b-catenin signaling pathway and promoted the invasion and metastasis of OSCC cells through miR-14 sponging based on cancer-associated exosome secretion. |
| Pubmed ID | 32102563 |
| Year | 2020 |
| Title | Long non-coding RNA TIRY promotes tumor metastasis by enhancing epithelial-to-mesenchymal transition in oral cancer |
External Links
| Links for TIRY | GenBank HGNC NONCODE |
| Links for oral squamous cell carcinoma | OMIM COSMIC |