Basic Information
| LncRNA/CircRNA Name | TINCR |
| Synonyms | TINCR, LINC00036, NCRNA00036, PLAC2, onco-lncRNA-16 |
| Region | GRCh38_19:5558167-5578349 |
| Ensemble | ENSG00000223573 |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | gastric cancer |
| ICD-0-3 | C16 |
| Methods | qPCR etc. |
| Sample | gastric cancer tissues |
| Expression Pattern | differential expression |
| Function Description | A allele genotypes of rs8113645 and G allele genotypes of rs2288947 (rs8113645 GA and AA; rs2288947 AG and GG) were also significantly associated with decreased GC risk. Stratification analysis displayed that the correlations between GC risk and variant genotypes of both rs8113645 and rs2288947were more evident in younger individuals, men, nonsmokers, and individuals from rural areas. We also demonstrated that rs8113645 GA+AA genotype carriers had lower TINCR mRNA expression levels compared with common genotype in both normal and GC tissues. |
| Pubmed ID | 27893425 |
| Year | 2016 |
| Title | Tag SNPs of long non-coding RNA TINCR affect the genetic susceptibility to gastric cancer in a Chinese population. |
External Links
| Links for TINCR | GenBank HGNC NONCODE |
| Links for gastric cancer | OMIM COSMIC |