Basic Information
| LncRNA/CircRNA Name | TINCR |
| Synonyms | TINCR, LINC00036, NCRNA00036, PLAC2, onco-lncRNA-16 |
| Region | GRCh38_19:5558167-5578349 |
| Ensemble | ENSG00000223573 |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | hepatocellular carcinoma |
| ICD-0-3 | C22.0 |
| Methods | qPCR, Western blot etc. |
| Sample | HCC tissues, cell line (HUH7) |
| Expression Pattern | up-regulated |
| Function Description | TINCR was significantly up-regulated in HCC. the associations of TINCR with clinicopathological characteristics, disease-free survival (DFS) and overall survival (OS) of patients were further evaluated. high TINCR expression was significantly correlated with tumor size,tumor differentiation status, TNM stage, and vascular invasion. TINCR was demonstrated as a direct target of miR-137 and miR-133a, and was suppressed by miR-137/miR-133a. |
| Pubmed ID | 28546230 |
| Year | 2017 |
| Title | TINCR expression is associated with unfavorable prognosis in patients with hepatocellular carcinoma. |
External Links
| Links for TINCR | GenBank HGNC NONCODE |
| Links for hepatocellular carcinoma | OMIM COSMIC |