Basic Information
| LncRNA/CircRNA Name | TINCR |
| Synonyms | TINCR, LINC00036, NCRNA00036, PLAC2, onco-lncRNA-16 |
| Region | GRCh38_19:5558167-5578349 |
| Ensemble | ENSG00000223573 |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | prostate cancer |
| ICD-0-3 | C61.9 |
| Methods | qPCR, Western blot |
| Sample | prostate cancer tissue, cell lines (LNCaP, PC3, DU145, 22Rv1, RWPE-1, P69) |
| Expression Pattern | down-regulated |
| Function Description | low-expression TINCR was observed in prostate cancer, and correlated with advanced clinical T stage, lymph node involvement, distant metastasis, high Gleason score and poor prognosis in prostate cancer patient. TINCR inhibits prostate cancer cell proliferation, migration and invasion via suppressing TRIP13 expression. |
| Pubmed ID | 30154672 |
| Year | 2018 |
| Title | LncRNA TINCR is associated with clinical progression and serves as tumor suppressive role in prostate cancer. |
External Links
| Links for TINCR | GenBank HGNC NONCODE |
| Links for prostate cancer | OMIM COSMIC |