Basic Information
| LncRNA/CircRNA Name | TDRG1 |
| Synonyms | NA |
| Region | GRCh38_6:40334954-40379887 |
| Ensemble | ENSG00000204091 |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | non small cell lung cancer |
| ICD-0-3 | C34 |
| Methods | qRT-PCR, RIP |
| Sample | NSCLC tissues,cell lines |
| Expression Pattern | up-regulated |
| Function Description | TDRG1 is significantly overregulated in NSCLC tissues and cell lines.lncRNA TDRG1 facilitates the progression of NSCLC via interacting with miR-873-5p and positively regulates the expression of ZEB1. |
| Pubmed ID | 31742752 |
| Year | 2019 |
| Title | LncRNA TDRG1 promotes the metastasis of NSCLC cell through regulating miR-873-5p/ZEB1 axis |
External Links
| Links for TDRG1 | GenBank HGNC NONCODE |
| Links for non small cell lung cancer | OMIM COSMIC |