Basic Information
| LncRNA/CircRNA Name | TDRG1 |
| Synonyms | NA |
| Region | GRCh38_6:40334954-40379887 |
| Ensemble | ENSG00000204091 |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | cervical cancer |
| ICD-0-3 | C53 |
| Methods | qRT-PCR, Western blot |
| Sample | CC tissues, cell lines (HeLa, Caski, SiHa, C-33A) |
| Expression Pattern | up-regulated |
| Function Description | TDRG1 acts as cancer promoter in CC through promoting cell proliferation, migration, invasion, and EMT process to modulate SOX4 expression through adsorbing miR-214-5p. |
| Pubmed ID | 32106739 |
| Year | 2020 |
| Title | LncRNA TDRG1 promotes the proliferation, migration, and invasion of cervical cancer cells by sponging miR-214-5p to target SOX4 |
External Links
| Links for TDRG1 | GenBank HGNC NONCODE |
| Links for cervical cancer | OMIM COSMIC |