Basic Information
| LncRNA/CircRNA Name | CASC11 |
| Synonyms | NA |
| Region | GRCh38_8:127686343-127733967 |
| Ensemble | ENSG00000249375 |
| Refseq | NR_117101 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | small cell lung cancer |
| ICD-0-3 | C56.9 |
| Methods | qPCR, Western blot |
| Sample | Human SCLC cell lines SHP-77 (ATCC? CRL-2195), DMS 79 (ATCC? CRL-2049), H345 (ATCC? HTB-180), DMS 53 (ATCC? CRL-2062), H446(ATCC? HTB-171) and H1341 (ATCC? CRL-5864) |
| Expression Pattern | up-regulated |
| Function Description | Plasma lncRNA CASC11 and TGF-?1 mRNA were upregulated in SCLC patients |
| Pubmed ID | 30965130 |
| Year | 2019 |
| Title | LncRNA CASC11 promotes TGF-?1, increases cancer cell stemness and predicts postoperative survival in small cell lung cancer. |
External Links
| Links for CASC11 | GenBank HGNC NONCODE |
| Links for small cell lung cancer | OMIM COSMIC |