Basic Information
| LncRNA/CircRNA Name | TCONS_00018436 |
| Synonyms | NA |
| Region | NA |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | hypopharyngeal squamous cell carcinoma |
| ICD-0-3 | C13 |
| Methods | qPCR etc. |
| Sample | hypopharyngeal squamous cell carcinoma tissues, cell lines (HSCC, FaDu and RS-FaDu) |
| Expression Pattern | up-regulated |
| Function Description | The significant upregulation of TCONS_00018436 in relapsed tumor samples was found. Depletion of TCONS_00018436 significantly sensitized RS-FaDu cells to the indicated doses of radiation (* P < 0.05), indicating that upregulated TCONS_00018436 might control radioresistance of HSCC cells during exposure to radiation. |
| Pubmed ID | 28487500 |
| Year | 2017 |
| Title | Time-course differential lncRNA and mRNA expressions in radioresistant hypopharyngeal cancer cells. |
External Links
| Links for TCONS_00018436 | GenBank HGNC NONCODE |
| Links for hypopharyngeal squamous cell carcinoma | OMIM COSMIC |