Basic Information
| LncRNA/CircRNA Name | TCONS_00007503 |
| Synonyms | RP11-315A17.1 |
| Region | GRCh38_4:31350284-31351725 |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | acute myeloid leukemia |
| ICD-0-3 | NA |
| Methods | Microarray, qPCR etc. |
| Sample | cell lines (K562 and NB4) |
| Expression Pattern | down-regulated |
| Function Description | In this study, we expand the analysis of CEBPA transcriptional targets to the newly identified class of long non-coding RNAs. We show that lncRNAs are a main component of the transcriptional program driven by C/EBPa and that many of these are also induced during granulocytic differentiation of AML cell lines supporting their relevance in proliferation arrest and differentiation. |
| Pubmed ID | 25252716 |
| Year | 2014 |
| Title | CEBPA-regulated lncRNAs, new players in the study of acute myeloid leukemia. |
External Links
| Links for TCONS_00007503 | GenBank HGNC NONCODE |
| Links for acute myeloid leukemia | OMIM COSMIC |