Basic Information
| LncRNA/CircRNA Name | TCL6 |
| Synonyms | T-cell leukemia/lymphoma 6 |
| Region | GRCh38_14:95650498-95679833 |
| Ensemble | ENSG00000187621 |
| Refseq | NR_028288 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | B cells , CD8+ T cells, CD4+ T cells, neutrophils, and dendritic cells | Survival | ||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | breast cancer |
| ICD-0-3 | C50 |
| Methods | other |
| Sample | TCGA |
| Expression Pattern | down-regulated |
| Function Description | low lncRNA TCL6 expression was correlated with worse survival, especially for PR-negative and luminal B breast cancer patients. lncRNA TCL6 regulated tumor-associated B cells, CD8+ T cells, CD4+ T cells, neutrophils, and DCs. |
| Pubmed ID | 31960363 |
| Year | 2020 |
| Title | lncRNA TCL6 correlates with immune cell infiltration and indicates worse survival in breast cancer |
External Links
| Links for TCL6 | GenBank HGNC NONCODE |
| Links for breast cancer | OMIM COSMIC |