Basic Information
| LncRNA/CircRNA Name | TC0101686 |
| Synonyms | NA |
| Region | NA |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | epithelial ovarian cancer |
| ICD-0-3 | C56.9 |
| Methods | Microarray, qPCR etc. |
| Sample | epithelial ovarian cancer tissues, cell lines (SKOV3 etc.) |
| Expression Pattern | down-regulated |
| Function Description | Notably, three candidates (TC0100223, TC0101686 and TC0101441) were aberrantly expressed in ERa-positive compared to ERa-negative EOC tissues, showing correlations with some malignant cancer phenotypes such as advanced FIGO stage and/or high histological grade. Furthermore, multivariate analysis indicated that TC0101441 was an independent prognostic factor for overall survival. |
| Pubmed ID | 24481591 |
| Year | 2014 |
| Title | Expression and clinical significance of estrogen-regulated long non-coding RNAs in estrogen receptor a-positive ovarian cancer progression. |
External Links
| Links for TC0101686 | GenBank HGNC NONCODE |
| Links for epithelial ovarian cancer | OMIM COSMIC |