Basic Information
| LncRNA/CircRNA Name | TC0101441 |
| Synonyms | NA |
| Region | GRCh38_1:204141408-204143009 |
| Ensemble | ENSG00000230550 |
| Refseq | NR_123739 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | epithelial ovarian cancer |
| ICD-0-3 | C56.9 |
| Methods | Microarray, qPCR, RNAi, Western blot etc. |
| Sample | epithelial ovarian cancer tissues, cell lines (SKOV3, A2780, PEO1 etc.) |
| Expression Pattern | up-regulated |
| Function Description | The results showed that ERa-positive tissues had higher expression of TC0101441 and lower expression TC0101686. Low-expression of TC0101686 was significantly related to ERa-positive EOC tissues with advanced FIGO stage, while high-expression of TC0101441 was closely correlated with advanced FIGO stage, high histological grade and lymph node metastasis. |
| Pubmed ID | 24380700 |
| Year | 2014 |
| Title | Effects of oestrogen on long noncoding RNA expression in oestrogen receptor alpha-positive ovarian cancer cells. |
External Links
| Links for TC0101441 | GenBank HGNC NONCODE |
| Links for epithelial ovarian cancer | OMIM COSMIC |