Basic Information
| LncRNA/CircRNA Name | TALNEC2 |
| Synonyms | LINC01116, TALNEC2 |
| Region | GRCh38_2:176629589-176637931 |
| Ensemble | ENSG00000163364 |
| Refseq | NR_040001 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | glioma |
| ICD-0-3 | NA |
| Methods | qPCR, Western blot etc. |
| Sample | cell lines (A172, U87) |
| Expression Pattern | up-regulated |
| Function Description | TALNEC2 was highly expressed in GBM with poor prognosis, in GBM specimens derived from short-term survivors and in glioma cells and glioma stem cells.Two of the downregulated miRNAs,miR-21 and miR-191, mediated some of TALNEC2 effects on the stemness and mesenchymal transformation of GSCs. |
| Pubmed ID | 28423669 |
| Year | 2017 |
| Title | The novel long non-coding RNA TALNEC2, regulates tumor cell growth and the stemness and radiation response of glioma stem cells |
External Links
| Links for TALNEC2 | GenBank HGNC NONCODE |
| Links for glioma | OMIM COSMIC |