Basic Information
| LncRNA/CircRNA Name | CAR10 |
| Synonyms | ADAM12, ADAM12-OT1, CAR10, MCMP, MCMPMltna, MLTN, MLTNA |
| Region | GRCh38_10:126012381-126388455 |
| Ensemble | ENSG00000148848 |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | uterine leiomyoma |
| ICD-0-3 | C57.4 |
| Methods | Microarray, qPCR, Cell proliferation assay etc. |
| Sample | uterine leiomyomas tissues, cell line (DD-HLM) |
| Expression Pattern | up-regulated |
| Function Description | In our microarray result, Intergenic 10 was dramatically upregulated in ULMs, with a 9-fold enrichment in small tumors and a 15-fold enrichment in large tumors. qPCR result confirmed the upregulation of Intergenic 10 in ULMs. It was more highly expressed in leiomyomas than in normal tissues in 28 of 30 cases. |
| Pubmed ID | 25268745 |
| Year | 2014 |
| Title | Integrated analysis of long noncoding RNAs and mRNAs reveals their potential roles in the pathogenesis of uterine leiomyomas. |
External Links
| Links for CAR10 | GenBank HGNC NONCODE |
| Links for uterine leiomyoma | OMIM COSMIC |