Basic Information
| LncRNA/CircRNA Name | SUMO1P3 |
| Synonyms | NA |
| Region | GRCh38_1:160317403-160317706 |
| Ensemble | ENSG00000235082 |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | pancreatic cancer |
| ICD-0-3 | C25 |
| Methods | qPCR, Western blot, RNAi, other |
| Sample | pancreatic cancer tissues and cell lines (BxPC-3, PANC-1, MiaPaCa-2, and ASPC-1) |
| Expression Pattern | up-regulated |
| Function Description | Additionally, the data indicated that the increased expression of SUMO1P3 is significantly associated with tumor progression and the poor survival of patients with pancreatic cancer. Furthermore, the present study identified that SUMO1P3 knockdown may suppress the proliferation, migration and invasion of pancreatic cancer cells. Additionally, downregulation of SUMO1P3 suppressed the epithelial-mesenchymal transition (EMT) and increased the expression of epithelial cadherin, and decreased the expression of neuronal cadherin, vimentin and ?-catenin. |
| Pubmed ID | 30333879 |
| Year | 2018 |
| Title | Long Non-Coding RNA SUMO1P3 May Promote Cell Proliferation, Migration, and Invasion of Pancreatic Cancer via EMT Signaling Pathway |
External Links
| Links for SUMO1P3 | GenBank HGNC NONCODE |
| Links for pancreatic cancer | OMIM COSMIC |