Basic Information
| LncRNA/CircRNA Name | SUMO1P3 |
| Synonyms | NA |
| Region | GRCh38_1:160317403-160317706 |
| Ensemble | ENSG00000235082 |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | hepatocellular carcinoma |
| ICD-0-3 | C22.0 |
| Methods | qPCR |
| Sample | hepatocellular carcinoma tissues, cell lines (MHCC97L, SMMC7721, HuH-7, HepG2, and Hep-3B) |
| Expression Pattern | up-regulated |
| Function Description | SUMO1P3 was significantly upregulated in HCC tissues and cells. Besides, SUMO1P3 was highly expressed in HCC patients with higher TNM stage. Furthermore, SUMO1P3 knockdown markedly suppressed cell proliferation, colony formation ability, and cell invasiveness, promoted apoptosis, and enhanced radiosensitivity of HCC cells. |
| Pubmed ID | 29905911 |
| Year | 2018 |
| Title | Knockdown of SUMO1P3 Represses Tumor Growth and Invasion and Enhances Radiosensitivity in Hepatocellular Carcinoma |
External Links
| Links for SUMO1P3 | GenBank HGNC NONCODE |
| Links for hepatocellular carcinoma | OMIM COSMIC |