Basic Information
| LncRNA/CircRNA Name | SRA |
| Synonyms | SRA1, SRA, SRAP, STRAA1, pp7684 |
| Region | GRCh38_5:140537340-140558252 |
| Ensemble | ENSG00000213523 |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | endometrial cancer |
| ICD-0-3 | NA |
| Methods | qRT-PCR, Luciferase reporter assay, Western blot analysis |
| Sample | Tissue samples,ECC-1 and Ishikawa EC cell lines |
| Expression Pattern | up-regulated |
| Function Description | Expression levels of SRA were upregulated in endometrial cancer tissues compared to those in adjacent control tissues.SRA is involved in proliferation, migration, and invasion of endometrial cancer cells by increasing the expression of EIF4E-BP1 and activity of Wnt/ ?-catenin signaling. |
| Pubmed ID | 31892849 |
| Year | 2020 |
| Title | Long Non-Coding RNA Steroid Receptor Activator Promotes the Progression of Endometrial Cancer via Wnt/ ?-Catenin Signaling Pathway |
External Links
| Links for SRA | GenBank HGNC NONCODE |
| Links for endometrial cancer | OMIM COSMIC |