Basic Information
| LncRNA/CircRNA Name | SOX2OT |
| Synonyms | SOX2-OT, NCRNA00043, SOX2OT |
| Region | GRCh38_3:180989762-181836880 |
| Ensemble | ENSG00000242808 |
| Refseq | NR_004053 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | cholangiocarcinoma |
| ICD-0-3 | NA |
| Methods | qPCR, in vitro knockdown etc. |
| Sample | cell line (RBE, QBC939, HIBEC), CCA tissues |
| Expression Pattern | up-regulated |
| Function Description | Upregulation of Sox2ot significantly associated with lymph node invasion , TNM stage and postoperative recurrence . |
| Pubmed ID | 29246536 |
| Year | 2017 |
| Title | Overexpressed long noncoding RNA Sox2ot predicts poor prognosis for cholangiocarcinoma and promotes cell proliferation and invasion. |
External Links
| Links for SOX2OT | GenBank HGNC NONCODE |
| Links for cholangiocarcinoma | OMIM COSMIC |