Basic Information
| LncRNA/CircRNA Name | SOX2OT |
| Synonyms | SOX2-OT, NCRNA00043, SOX2OT |
| Region | GRCh38_3:180989762-181836880 |
| Ensemble | ENSG00000242808 |
| Refseq | NR_004053 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | gastric cancer |
| ICD-0-3 | C16 |
| Methods | qPCR etc. |
| Sample | gastric cancer tissues |
| Expression Pattern | down-regulated |
| Function Description | Sox2ot expression levels were decreased in cancerous tissues compared to their corresponding non-cancerous controls. Sox2ot expression was associated with T stage, distant metastasis and differentiation. |
| Pubmed ID | 27874951 |
| Year | 2016 |
| Title | High expression of long noncoding RNA Sox2ot is associated with the aggressive progression and poor outcome of gastric cancer. |
External Links
| Links for SOX2OT | GenBank HGNC NONCODE |
| Links for gastric cancer | OMIM COSMIC |