Basic Information
| LncRNA/CircRNA Name | SOX2OT |
| Synonyms | SOX2-OT, NCRNA00043, SOX2OT |
| Region | GRCh38_3:180989762-181836880 |
| Ensemble | ENSG00000242808 |
| Refseq | NR_004053 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | cervical cancer |
| ICD-0-3 | C53 |
| Methods | qPCR, Western blot etc. |
| Sample | cell lines(HaCaT, HeLa, C-33A, SiHa) |
| Expression Pattern | differential expressed |
| Function Description | Differential expression of SOX2OT transcripts and SOX2 in cervical cancer cells. Knockdown of SOX2OT inhibited the growth, migration and invasion of C-33A and SiHa cells |
| Pubmed ID | 32286144 |
| Year | 2020 |
| Title | LncRNA SOX2OT affects cervical cancer cell growth, migration and invasion by regulating SOX2. |
External Links
| Links for SOX2OT | GenBank HGNC NONCODE |
| Links for cervical cancer | OMIM COSMIC |