Basic Information
| LncRNA/CircRNA Name | SOX21-AS1 |
| Synonyms | NA |
| Region | GRCh38_13:94712716-94716246 |
| Ensemble | ENSG00000227640 |
| Refseq | NR_046514 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | glioma |
| ICD-0-3 | NA |
| Methods | qRT-PCR, Western blot |
| Sample | glioma tissues,cell lines (U251, U118, LN229, U87 and SHG44) |
| Expression Pattern | up-regulated |
| Function Description | SOX21-AS1 was upregulated in glioma tissues and cells.SOX21-AS1/miR-144-3p/PAK7 axis played an oncogenic role in glioma cells by regulatin ??atenin pathway, which suggests a rational therapeutic strategy for glioma. |
| Pubmed ID | 31973536 |
| Year | 2019 |
| Title | Long non-coding RNA SOX21-AS1 promotes cell proliferation and invasion through upregulating PAK7 expression by sponging miR-144-3p in glioma cells |
External Links
| Links for SOX21-AS1 | GenBank HGNC NONCODE |
| Links for glioma | OMIM COSMIC |