Basic Information
| LncRNA/CircRNA Name | CACS15 |
| Synonyms | NA |
| Region | NA |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | ovarian cancer |
| ICD-0-3 | C56.9 |
| Methods | qRT-PCR, Western blot |
| Sample | OC tissues,cell lines |
| Expression Pattern | up-regulated |
| Function Description | CACS15 was upregulated in OC tissues and cell lines relative to matched ones.LncRNA CACS15 inhibits the expression of APC by recruiting EZH2, thus accelerating the progression of ovarian cancer as an oncogene. |
| Pubmed ID | 31737207 |
| Year | 2019 |
| Title | LncRNA CACS15 accelerates the malignant progression of ovarian cancer through stimulating EZH2-induced inhibition of APC |
External Links
| Links for CACS15 | GenBank HGNC NONCODE |
| Links for ovarian cancer | OMIM COSMIC |