Basic Information
LncRNA/CircRNA Name | SNHG7 |
Synonyms | SNHG7, NCRNA00061 |
Region | GRCh38_9:136721366-136728184 |
Ensemble | ENSG00000233016 |
Refseq | NR_003672 |
Classification Information
Regulatory Mechanism | Biological Function | Clinical Application | |||
---|---|---|---|---|---|
TF | Immune | Survival | |||
Enhancer | Apoptosis | Drug | |||
Variant | Cell Growth | Circulating | |||
MiRNA | EMT | Metastasis | |||
Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
Cancer Name | osteosarcoma |
ICD-0-3 | NA |
Methods | qRT-PCR, Luciferase reporter assay, Western blot analysis |
Sample | The OS cell lines (MG63, SaOS2, HOS, and 143B) and human osteoblastic cell line (hFOB1.19), The OS tissues and corresponding relative normal tissues |
Expression Pattern | up-regulated |
Function Description | the LncRNA SNHG7 is upregulated during the development of OS via inhibition of tumor suppressor miR-34s signals. |
Pubmed ID | 29989838 |
Year | 2018 |
Title | Long Noncoding RNA SNHG7 Promotes the Tumor Growth and Epithelial-to-Mesenchymal Transition via Regulation of miR-34a Signals in Osteosarcoma. |
External Links
Links for SNHG7 | GenBank HGNC NONCODE |
Links for osteosarcoma | OMIM COSMIC |