Basic Information
| LncRNA/CircRNA Name | CACNA1G-AS1 |
| Synonyms | NA |
| Region | GRCh38_17:50556207-50562108 |
| Ensemble | ENSG00000250107 |
| Refseq | NR_038439 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | colorectal cancer |
| ICD-0-3 | C19.9 |
| Methods | qRT-PCR, Western blot, RIP |
| Sample | CRC tissues,CRC cell lines and colonic epithelial cell line |
| Expression Pattern | up-regulated |
| Function Description | CACNA1G-AS1 was upregulated in CRC tissues compared to adjacent normal ones.CACNA1G-AS1 was upregulated in CRC tissues compared to adjacent normal ones.Knockdown of CACNA1G-AS1 or EZH2 upregulated p53 level and decreased the recruitment ability of EZH2 on p53. |
| Pubmed ID | 31957825 |
| Year | 2020 |
| Title | Upregulated lncRNA CACNA1G-AS1 Aggravates the Progression of Colorectal Cancer by Downregulating p53 |
External Links
| Links for CACNA1G-AS1 | GenBank HGNC NONCODE |
| Links for colorectal cancer | OMIM COSMIC |