Basic Information
| LncRNA/CircRNA Name | SNHG7 |
| Synonyms | SNHG7, NCRNA00061 |
| Region | GRCh38_9:136721366-136728184 |
| Ensemble | ENSG00000233016 |
| Refseq | NR_003672 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | lung cancer |
| ICD-0-3 | C34 |
| Methods | qPCR, RNAi, Western blot, Luciferase reporter assay, Cell proliferation assay etc. |
| Sample | lung cancer tissues, cell lines (H125, 95D and A594) |
| Expression Pattern | up-regulated |
| Function Description | The expression levels of lncRNA-SNHG7 mRNA and protein obviously increased in lung cancer tissues compared to adjacent non-cancerous tissues. Silence of lncRNA-SNHG7 by siRNA repressed the level of FAIM2 protein and suppressed cell proliferation, migration and invasion and accelerated apoptosis of A594 cells in vitro. lncRNA-SNHG7 promotes the proliferation, migration and invasion, and inhibits apoptosis of lung cancer cells by enhancing the FAIM2 expression. |
| Pubmed ID | 27666964 |
| Year | 2016 |
| Title | lncRNA-SNHG7 promotes the proliferation, migration and invasion and inhibits apoptosis of lung cancer cells by enhancing the FAIM2 expression. |
External Links
| Links for SNHG7 | GenBank HGNC NONCODE |
| Links for lung cancer | OMIM COSMIC |