Basic Information
| LncRNA/CircRNA Name | SNHG7 |
| Synonyms | NA |
| Region | GRCh38_9:136721366-136728184 |
| Ensemble | ENSG00000233016 |
| Refseq | NR_003672 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | cervical cancer |
| ICD-0-3 | C53 |
| Methods | RT-qPCR, Western blot |
| Sample | CC tissues and cell lines |
| Expression Pattern | up-regulated |
| Function Description | We found that SNHG7 was markedly enhanced in CC tissues and cell lines, and associated with poor clinical characteristics.SNHG7 upregulated JUND expression via miR-485-5p.SNHG7 promoted CC progression through miR-485-5p/JUND axis. In vitro, knockdown of SNHG7 inhibited CC cell proliferation, migration and invasion, as well as aggravated cell apoptosis. |
| Pubmed ID | 32161467 |
| Year | 2020 |
| Title | LncRNA SNHG7 Functions as an Oncogene in Cervical Cancer by Sponging miR-485-5p to Modulate JUND Expression |
External Links
| Links for SNHG7 | GenBank HGNC NONCODE |
| Links for cervical cancer | OMIM COSMIC |