Basic Information
| LncRNA/CircRNA Name | SNHG6 |
| Synonyms | NA |
| Region | GRCh38_8:66921684-66926398 |
| Ensemble | ENSG00000245910 |
| Refseq | NR_002599 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | 5-fluorouracil | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | colorectal cancer |
| ICD-0-3 | C19.9 |
| Methods | qPCR, western blot |
| Sample | CRC cell line |
| Expression Pattern | differential expression |
| Function Description | SNHG6 enhanced CRC cell resistance to 5-fluorouracil (5-FU), promoted autophagy, inhibited 5-FU-induced apoptosis, and increased 5-FU resistance in vivo. |
| Pubmed ID | 31516391 |
| Year | 2019 |
| Title | LncRNA SNHG6 promotes chemoresistance through ULK1-induced autophagy by sponging miR-26a-5p in colorectal cancer cells. |
External Links
| Links for SNHG6 | GenBank HGNC NONCODE |
| Links for colorectal cancer | OMIM COSMIC |