Basic Information
| LncRNA/CircRNA Name | SNHG6 |
| Synonyms | NA |
| Region | GRCh38_8:66921684-66926398 |
| Ensemble | ENSG00000245910 |
| Refseq | NR_002599 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | pancreatic cancer |
| ICD-0-3 | C25 |
| Methods | qPCR, Luciferase reporter assay, RIP etc |
| Sample | PC tissues, cell lines (MIAPaCa-2, BxPC-3, Capan-1, and Panc-1) |
| Expression Pattern | up-regulated |
| Function Description | Compared with that in normal tissues, SNHG6 was highly expressed in PC tissues.Silencing SNHG6 might ameliorate PC through inhibition of FUBP1 by sponging miR-26a-5p, thus providing further supporting evidence for its use in PC treatment. |
| Pubmed ID | 32265427 |
| Year | 2020 |
| Title | Long Non-Coding RNA Small Nucleolar RNA Host Gene 6 Aggravates Pancreatic Cancer Through Upregulation of Far Upstream Element Binding Protein 1 by Sponging microRNA-26a-5p |
External Links
| Links for SNHG6 | GenBank HGNC NONCODE |
| Links for pancreatic cancer | OMIM COSMIC |